Most laser questions are really materials questions. A CO2 laser handles non-metals — wood and plywood, acrylic, genuine leather, paper and card, fabric, felt, cork, and laser-safe rubber — while cutting metal needs a fiber laser, and glass or ceramic engraves rather than cuts. Match the material to the laser type and most jobs go smoothly.
One rule never bends: never laser-cut PVC or vinyl. Burning PVC releases chlorine gas and hydrochloric acid — toxic to breathe and corrosive to the machine’s frame, rails, and optics — and the damage is gradual and permanent even with ventilation running. The same caution covers unknown plastics, PVC-based faux leather, and polycarbonate (Lexan). When in doubt, verify the exact material with the supplier before it goes in the machine.
The rest of shop safety is habit, not hardware: run exhaust on every job, keep air assist on, and never leave a running laser unattended. The answers below cover what’s safe, what isn’t, and how to tell the difference — each links to a full reference page where one exists. For how specific materials actually cut and engrave, see the laser cutting and laser engraving topics, or head back to all laser FAQs.